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Effects of comprehensive therapy based on traditional Chinese medicine patterns on older patients with

Minghang Wang,Jiansheng Li,Suyun Li,Yang Xie

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 368-375 doi: 10.1007/s11684-014-0360-0

Abstract: evaluate the efficacy of comprehensive therapy based on traditional Chinese medicine (TCM) patterns on older

Keywords： chronic obstructive pulmonary disease     older adult     clinical trial     Bu-Fei Jian-Pi granules     Bu-Fei Yi-Shen    

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Reducing biliary complications in adult-to-adult living donor liver transplantation using right lobe

YAN Lunan, WEN Tianfu, WANG Wentao, YANG Jiayin, XU Mingqing, CHEN Zheyu, WU Hong

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 130-133 doi: 10.1007/s11684-008-0024-z

Abstract: is to summarize our experience of using right lobe liver grafts to reduce biliary complications in adult-to-adultFrom January 2002 to October 2007, 124 adult patients underwent living donor liver transplantation using

Keywords： microsurgical     October     improved     success     transplantation    

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Advances in immunopathogenesis of adult immune thrombocytopenia

Xinguang Liu, Yu Hou, Jun Peng

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 418-424 doi: 10.1007/s11684-013-0297-8

Abstract:

Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by immune-mediated accelerated platelet destruction and/or suppressed platelet production. Although the development of autoantibodies against platelet glycoproteins remains central in the pathophysiology of ITP, several abnormalities involving the cellular mechanisms of immune modulation have been identified, and the pathways behind the immune-mediated destruction of platelets have opened new avenues for the design of specific immunotherapies in an attempt to reduce the platelet destruction. This review is primarily focused on the recent literature with respect to immunopathological mechanisms in patients with ITP.

Keywords： primary immune thrombocytopenia     B lymphocytes     T lymphocytes     antigen-presenting cells     cytokines    

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Preliminary experience in adult-to-adult living donor liver transplantation in a single center in China

YAN Lunan, ZENG Yong, WEN Tianfu, ZHAO Jichun, WANG Wentao, YANG Jiayin, XU Mingqing, MA Yukui, CHEN Zheyu, LIU Jiangwen, WU Hong

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 136-141 doi: 10.1007/s11684-007-0026-2

Abstract: The aim of this paper is to report the authors experience in performing adult-to-adult living donorFrom January 2002 to September 2006, 56 adult patients underwent LDLT using right lobe grafts at the
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mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in embryonic and adult

Frontiers of Medicine   Pages 939-956 doi: 10.1007/s11684-023-0987-9

Abstract: proportion of mononuclear diploid cardiomyocytes (MNDCMs), with regeneration potential, could persist in adultthe Myl4+Tnni1+ MNDCMs persisted in embryonic and adult

Keywords： mononuclear diploid cardiomyocytes     cell–cell communication     cardiac fibroblast     single-cell RNA sequencing     cardiac regeneration    

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Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis

Jian Liu, Weiming Wang

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 333-339 doi: 10.1007/s11684-017-0564-1

Abstract: Adult-onset FSGS/NS is often associated with low response to steroid treatment and immunosuppressiveIn this review, we focus on the recently identified genes in the adult-onset NS and FSGS and discuss

Keywords： nephrotic syndrome     focal segmental glomerulosclerosis     genetic    

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Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 240-262 doi: 10.1007/s11684-022-0936-z

Abstract: Detailed characterizations of genomic alterations have not identified subtype-specific vulnerabilities in adultco-expressed with EGFR or PDGFRA (EM or PM), we recently proposed an EM/PM classification scheme for adultThus, while genetic makeup may change during progression and/or within different tumor areas, adult gliomas

Keywords： glioma progression     molecular classification     EM/PM subtyping     intratumor heterogeneity    

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Emergency adult living donor right lobe liver transplantation for fulminant hepatic failure

ZHANG Feng, WANG Xuehao, LI Xiangcheng, KONG Lianbao, SUN Beicheng, LI Guoqiang, QIAN Xiaofen, CHEN Feng, WANG Ke, LU Sheng, PU Liyong, LU Ling

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 282-286 doi: 10.1007/s11684-007-0054-y

Abstract: Nine cases of adult right lobe LDLT were performed in our department from September 2002 to August 2005Emergency adult living-donor liver transplantation is an effective treatment for fulminant hepatitis

Keywords： alimentary     abnormal     hemorrhage     principal     different    

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Efficacy and prognostic factors of imatinib plus CALLG2008 protocol in adult patients with newly diagnosed

Yinjun Lou, Yafang Ma, Chenyin Li, Sansan Suo, Hongyan Tong, Wenbin Qian, Wenyuan Mai, Haitao Meng, Wenjuan Yu, Liping Mao, Juyin Wei, Weilei Xu, Jie Jin

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 229-238 doi: 10.1007/s11684-017-0506-y

Abstract: CALLG2008 protocol was developed by the Chinese Acute Lymphoblastic Leukemia Cooperative Group for adultWe retrospectively analyzed 153 newly diagnosed adult patients with Philadelphia chromosome (Ph)-positive

Keywords： Philadelphia chromosome     acute lymphoblastic leukemia     imatinib     CALLG2008    

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Superiority of allogeneic hematopoietic stem cell transplantation to nilotinib and dasatinib for adult

Lanping Xu,Huanling Zhu,Jianda Hu,Depei Wu,Hao Jiang,Qian Jiang,Xiaojun Huang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 304-311 doi: 10.1007/s11684-015-0400-4

Abstract: These results indicated that allo-HSCT may be superior to nilotinib and dasatinib for adult patients

Keywords： chronic myeloid leukemia     imatinib     dasatinib     nilotinib     allogeneic hematopoietic stem cell transplantation    

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with post-transplantation cyclophosphamide for allogeneic peripheral stem cell transplantation for adult

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 108-115 doi: 10.1007/s11684-019-0730-8

Abstract: This single-arm phase II clinical trial (NCT01435447) involving 31 adult patients was conducted from

Keywords： post-transplantation cyclophosphamide     allogeneic hematopoietic stem cell transplantation     lymphoid malignancies    

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Lung function and air pollution exposure in adults with asthma in Beijing: a 2-year longitudinal panel study

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 574-583 doi: 10.1007/s11684-021-0882-1

Abstract: The effect of air pollution on the lung function of adults with asthma remains unclear to date. This study followed 112 patients with asthma at 3-month intervals for 2 years. The pollutant exposure of the participants was estimated using the inverse distance weight method. The participants were divided into three groups according to their lung function level at every visit. A linear mixed-effect model was applied to predict the change in lung function with each unit change in pollution concentration. Exposure to carbon monoxide (CO) and particles less than 2.5 micrometers in diameter (PM2.5) was negatively associated with large airway function in participants. In the severe group, exposure to chronic sulfur dioxide (SO2) was negatively associated with post-bronchodilator forced expiratory flow at 50%, between 25% and 75% of vital capacity % predicted (change of 95% CI per unit: −0.34 (−0.55, −0.12), −0.24 (−0.44, −0.03), respectively). In the mild group, the effect of SO2 on the small airways was similar to that in the severe group, and it was negatively associated with large airway function. Exposure to CO and PM2.5 was negatively associated with the large airway function of adults with asthma. The negative effects of SO2 were more evident and widely observed in adults with severe and mild asthma than in adults with moderate asthma. Patients with asthma react differently to air pollutants as evidenced by their lung function levels.

Keywords： lung function     asthma     air pollution     adult    

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Adult Mammalian Neurogenesis: Hopes and Challenges in the Repair of Spinal Cord Injury

Zhaoyang Yang, Wen Zhao, Yudan Gao, Hongmei Duan, Peng Hao,  Fei Hao, Xiaoguang Li

Engineering 2021, Volume 7, Issue 12,   Pages 1713-1714 doi: 10.1016/j.eng.2021.09.009

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Muscle Weight and Postprandial Protein Synthesis of Skeletal Muscle by Promoting the mTOR Pathway in Adult

Bo Zhang, Licui Chu, Hong Liu, Chunyuan Xie, Shiyan Qiao, Xiangfang Zeng

Engineering 2017, Volume 3, Issue 5,   Pages 760-765 doi: 10.1016/J.ENG.2017.03.008

Abstract: investigate whether leucine supplementation would increase the synthesis rate of protein and muscle weight in adultIn conclusion, when protein is chronically restricted in adult rat diets, leucine supplementation moderately

Keywords： Low-protein diet     Leucine     Growth performance     Muscle weight     Protein synthesis     Adult rats    

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Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 139-143 doi: 10.1007/s11684-019-0736-2

Abstract: The rationale for the antibiotic treatment of viral community-acquired pneumonia (CAP) in adults was analyzed to develop a clinical reference standard for this condition. Clinical data from 166 patients diagnosed with viral pneumonia across 14 hospitals in Beijing from November 2010 to December 2017 were collected. The indications for medications were evaluated, and the rationale for the use of antibiotics was analyzed. A total of 163 (98.3%) patients with viral pneumonia were treated with antibiotics. A combination of C-reactive protein (CRP) and procalcitonin (PCT) was used as markers to analyze the possible indications for antibiotic use. With threshold levels set at 0.25 µg/L for PCT and 20 mg/L for CRP, the rate of unreasonable use of antibiotics was 55.2%. By contrast, at a CRP level threshold of 60 mg/L, the rate of antibiotic misuse was 77.3%. A total of 39 of the 163 (23.9%) patients did not meet the guidelines for drug selection for viral CAP in adults. The unreasonable use of antibacterial drugs for the treatment of viral CAP in adults is a serious concern. Clinicians must reduce the unnecessary use of antibiotics.

Keywords： adult     antibiotic     viral pneumonia    

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Title Author Date Type Operation

Effects of comprehensive therapy based on traditional Chinese medicine patterns on older patients with

Minghang Wang,Jiansheng Li,Suyun Li,Yang Xie

Journal Article

Reducing biliary complications in adult-to-adult living donor liver transplantation using right lobe

YAN Lunan, WEN Tianfu, WANG Wentao, YANG Jiayin, XU Mingqing, CHEN Zheyu, WU Hong

Journal Article

Advances in immunopathogenesis of adult immune thrombocytopenia

Xinguang Liu, Yu Hou, Jun Peng

Journal Article

Preliminary experience in adult-to-adult living donor liver transplantation in a single center in China

YAN Lunan, ZENG Yong, WEN Tianfu, ZHAO Jichun, WANG Wentao, YANG Jiayin, XU Mingqing, MA Yukui, CHEN Zheyu, LIU Jiangwen, WU Hong

Journal Article

mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in embryonic and adult

Journal Article

Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis

Jian Liu, Weiming Wang

Journal Article

Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Journal Article

Emergency adult living donor right lobe liver transplantation for fulminant hepatic failure

ZHANG Feng, WANG Xuehao, LI Xiangcheng, KONG Lianbao, SUN Beicheng, LI Guoqiang, QIAN Xiaofen, CHEN Feng, WANG Ke, LU Sheng, PU Liyong, LU Ling

Journal Article

Efficacy and prognostic factors of imatinib plus CALLG2008 protocol in adult patients with newly diagnosed

Yinjun Lou, Yafang Ma, Chenyin Li, Sansan Suo, Hongyan Tong, Wenbin Qian, Wenyuan Mai, Haitao Meng, Wenjuan Yu, Liping Mao, Juyin Wei, Weilei Xu, Jie Jin

Journal Article

Superiority of allogeneic hematopoietic stem cell transplantation to nilotinib and dasatinib for adult

Lanping Xu,Huanling Zhu,Jianda Hu,Depei Wu,Hao Jiang,Qian Jiang,Xiaojun Huang

Journal Article

with post-transplantation cyclophosphamide for allogeneic peripheral stem cell transplantation for adult

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Journal Article

Lung function and air pollution exposure in adults with asthma in Beijing: a 2-year longitudinal panel study

Journal Article

Adult Mammalian Neurogenesis: Hopes and Challenges in the Repair of Spinal Cord Injury

Zhaoyang Yang, Wen Zhao, Yudan Gao, Hongmei Duan, Peng Hao,  Fei Hao, Xiaoguang Li

Journal Article

Muscle Weight and Postprandial Protein Synthesis of Skeletal Muscle by Promoting the mTOR Pathway in Adult

Bo Zhang, Licui Chu, Hong Liu, Chunyuan Xie, Shiyan Qiao, Xiangfang Zeng

Journal Article

Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Journal Article